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Natural Hair Care Ingredient: Cacumen Platycladi Extract
Author : Naturalin Date : Click : times
In the current pursuit of “scalp health” and “anti‑hair loss” the irritation and side effects of synthetic chemicals are driving more consumers toward traditional botanicals. Its medicinal and hair-nourishing properties are documented in traditional Chinese medicine classics. The "Compendium of Materia Medica" also confirmed its efficacy in promoting hair growth and darkening gray hair.
Active Constituents
Modern phytochemical analyses reveal that Cacumen Platycladi Extract is rich in three major classes of bioactive substances, which collectively form the material basis for its hair‑protective effects:
· Flavonoids
· Volatile oils
· Terpenoids and lignans
How Does Cacumen Platycladi Extract Work?
1. Improving Microcirculation and Awakening Dormant Follicles
Studies have shown that Cacumen Platycladi Extract can relax vascular smooth muscle and increase blood‑oxygen perfusion in the dermal papilla zone, thereby shifting follicles from telogen (resting phase) back into anagen (growth phase). Animal experiments demonstrated that mice treated with the extract exhibited a significantly higher proportion of follicles in the anagen phase (Park et al., 2019).
2. Inhibiting 5α-Reductase and Blocking DHT Attack
A 2021 study published in the Journal of Ethnopharmacology clearly indicated that the total flavonoids from Cacumen Platycladi competitively inhibit type-II 5α--reductase activity, reducing the intrafollicular concentration of dihydrotestosterone (DHT) and thereby slowing follicular miniaturization. (Lee et al., 2021).
3. Anti-inflammatory and Antioxidant Actions-Fortifying the Scalp Barrier
Cedrol, a component of the volatile oil, significantly reduces levels of pro‑inflammatory cytokines such as TNF‑α and IL‑6, while flavonoids scavenge excessive reactive oxygen species (ROS), protecting follicular stem cells from damage. This dual protection provides a stable internal environment for hair growth.
Synergistic Formulations: Classic Compatible Ingredients with Cacumen Platycladi Extract
* Sapindus mukorossi fruit extract
* Polygonum multiflorum extract
* Angelica root extract
* Panax ginseng root extract
About Naturalin
Naturalin is rich of experience in natural ingredient additives for personal care products applications.We hold an invention patent for the production technology of *Cacumen Platycladi* extract and have a wealth of successful case studies. In addition, Naturalin's new factory has officially commenced production; with significantly enhanced capacity and efficiency, it ensures a stable supply of orders during peak periods.
References:
[1] Lee G, et al. Cacumen Platycladi inhibits 5α-reductase and promotes hair growth in androgenetic alopecia via modulation of androgen receptor signaling. Journal of Ethnopharmacology, 2021, 268: 113578.
[2] Park WS, et al. Antioxidant and anti-inflammatory effects of essential oil from Platycladus orientalis leaves in human dermal papilla cells. Korean Journal of Pharmacognosy, 2019, 50(2): 112-119.
[3] Zhang NN, et al. Flavonoids from Platycladus orientalis promote hair growth via Wnt/β-catenin signaling. Chinese Herbal Medicines, 2022, 14(1): 78-85.
Active Constituents
Modern phytochemical analyses reveal that Cacumen Platycladi Extract is rich in three major classes of bioactive substances, which collectively form the material basis for its hair‑protective effects:
· Flavonoids
· Volatile oils
· Terpenoids and lignans
How Does Cacumen Platycladi Extract Work?
1. Improving Microcirculation and Awakening Dormant Follicles
Studies have shown that Cacumen Platycladi Extract can relax vascular smooth muscle and increase blood‑oxygen perfusion in the dermal papilla zone, thereby shifting follicles from telogen (resting phase) back into anagen (growth phase). Animal experiments demonstrated that mice treated with the extract exhibited a significantly higher proportion of follicles in the anagen phase (Park et al., 2019).
2. Inhibiting 5α-Reductase and Blocking DHT Attack
A 2021 study published in the Journal of Ethnopharmacology clearly indicated that the total flavonoids from Cacumen Platycladi competitively inhibit type-II 5α--reductase activity, reducing the intrafollicular concentration of dihydrotestosterone (DHT) and thereby slowing follicular miniaturization. (Lee et al., 2021).
3. Anti-inflammatory and Antioxidant Actions-Fortifying the Scalp Barrier
Cedrol, a component of the volatile oil, significantly reduces levels of pro‑inflammatory cytokines such as TNF‑α and IL‑6, while flavonoids scavenge excessive reactive oxygen species (ROS), protecting follicular stem cells from damage. This dual protection provides a stable internal environment for hair growth.
Synergistic Formulations: Classic Compatible Ingredients with Cacumen Platycladi Extract
* Sapindus mukorossi fruit extract
* Polygonum multiflorum extract
* Angelica root extract
* Panax ginseng root extract
About Naturalin
Naturalin is rich of experience in natural ingredient additives for personal care products applications.We hold an invention patent for the production technology of *Cacumen Platycladi* extract and have a wealth of successful case studies. In addition, Naturalin's new factory has officially commenced production; with significantly enhanced capacity and efficiency, it ensures a stable supply of orders during peak periods.
References:
[1] Lee G, et al. Cacumen Platycladi inhibits 5α-reductase and promotes hair growth in androgenetic alopecia via modulation of androgen receptor signaling. Journal of Ethnopharmacology, 2021, 268: 113578.
[2] Park WS, et al. Antioxidant and anti-inflammatory effects of essential oil from Platycladus orientalis leaves in human dermal papilla cells. Korean Journal of Pharmacognosy, 2019, 50(2): 112-119.
[3] Zhang NN, et al. Flavonoids from Platycladus orientalis promote hair growth via Wnt/β-catenin signaling. Chinese Herbal Medicines, 2022, 14(1): 78-85.
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